Housewas a special blend of medical intrigue, dark humor, and a protagonist who defied the mold of a compassionate TV doctor. Dr. Gregory House was a brilliant diagnostician, sothe characters inHouseoverlooked his biting bedside manner and functional drug addiction. The medical procedural thrived on moral dilemmas, andthe best episodes ofHousefeatured the team in continuous debate about what constituted the ethical choice.Housewas loosely based on Sherlock Holmes, which is why it was one of the first modern medical shows to introduce to inject mystery and deductive logic into the genre.
If you’re a fan ofHouse, you might want to check out some of these more recent medical shows, including some ofthe best medical dramas. Whether you like the show for its medical mysteries, the romantic drama behind the scenes, or its rogue protagonist taking on the hospital system, these series will satisfy a craving foranyone who missesHouse. Many of these TV series are inspired byHouse, building on its legacy and even taking some of the elements fans loved further.
St. Denis Medical
Cast
St. Denis Medical follows a diverse team of doctors and nurses at an underfunded Oregon hospital as they manage patient care and maintain camaraderie amid challenging circumstances.
ThoughHouseis a medical drama, it often leaned into dark comedy, making it nearly a dramedy.St. Denis Medicalis NBC’s more lighthearted sitcom, but both shows acknowledge that medicine isn’t just about life-or-death decisions, it’s about the absurd, the frustrating, and the deeply human moments that happen in hospitals.
WhileHousefocused on one brilliant but misanthropic doctor solving medical puzzles,St. Denis Medicalembraces an ensemble of well-meaning but flawed doctors and nurses, showcasing the daily chaos with a lighter touch.Both series remind audiences that even in serious professions, humor is essential, whether it’s House’s biting sarcasm orSt. Denis Medical’s workplace antics.St. Denis’s renewal for season 2proves audiences still love seeing the lighter, chaotic side of healthcare.
Doc
Doc is a 2025 drama featuring Dr. Amy Larsen, who copes with a brain injury leaving her without memories of the last eight years. Relying on her estranged daughter and close friends, she confronts challenges in practicing medicine and personal life, struggling to regain lost expertise and connections.
Fox’s new seriesDochas a lot in common withHouse, particularly in its medical approach and the character of Dr. Amy Larsen, at least before her accident, who comes across as a more abrasive version of herself.Both Amy and House exhibit a relentless drive to solve complex medical cases, often believing they know best and breaking the rules ostensibly for the sake of their patients, although also to boost their own egos.
Like House, Amy is unorthodox, blunt, and determined, willing to go to extreme lengths to uncover the truth.
Like House, Amy is unorthodox, blunt, and determined, willing to go to extreme lengths to uncover the truth. WhileHousefollowed a more structured case-of-the-week format,Docleans into an overarching mystery with emotional and romantic entanglements. Fans ofHousewill appreciateDoc’s difficult medical decisions, emotional complexity, and Amy’s uncompromising commitment to her patients.Doc’s season 1 finale has a lot of unanswered questionsthat will hopefully be addressed in season 2.
8The Good Doctor (2017-2024)
A More Humanistic Approach To A Doctor Who Sees Things Differently
The Good DoctorandHouseboth centered on brilliant medical minds who struggled with social norms but ultimately improved patient outcomes because of their unique perspectives. Freddie Highmore’s Dr. Shaun Murphy, whose autism creates a communication barrier, often makes unintentional missteps, while House’s prickly demeanor is more of a conscious choice.David Shore, the creator ofHouse, also created this show, so it’s no surprise it explores similar territory and had a successful run, with 126 episodes overThe Good Doctor’s seven seasons.
All 11 House Actors Who Appear In The Good Doctor
As two beloved medical dramas, House and The Good Doctor resemble one another regarding actors who’ve taken on roles in both shows.
In some ways,The Good Doctorwas almost an emotional inverse ofHouse: Shaun is kind-hearted and trying his best, but still makes social faux pas, while House is jaded and often intentionally difficult. Yetboth challenged the medical system, had a gift so special exceptions were made for them, and solved cases no one else could. Their brilliance lay in how they thought differently, and both shows explore the tension between being right and being understood.
Mary Kills People
Mary Kills People is a Canadian drama series that follows Dr. Mary Harris, an ER doctor by day and an underground angel of death by night, who helps terminally ill patients end their lives on their own terms, while facing the challenges and dangers of her double life.
Mary Kills Peopleshared key thematic ground withHouse, especially in its exploration of morally gray areas in medicine. Dr. Mary Harris was an ER doctor by day and an underground provider of assisted suicides by night, an act that was illegal but rooted in compassion and patient autonomy. House, with his deep disdain for bureaucracy and reverence for logic over rules, would likely approve of Mary’s rebellion.
Mary Kills Peoplehas a 100% rating onRotten Tomatoes.
Both characters prioritize what they believe is right over what is legal or expected, often at great personal risk. This Canadian series, with just 18 episodes, delivers a sharp, ethically complex story about the limits of medical care, the weight of choice, and the humanity behind tough decisions, very much inHouse’s wheelhouse.
New Amsterdam
New Amsterdam is a medical drama series based on Eric Manheimer’s book Twelve Patients: Life and Death at Bellevue Hospital. Ryan Eggold stars as Dr. Max Goodwin, the newly appointed medical director of the New Amsterdam Medical Center. Over the course of five seasons, he works tirelessly to bring change to the neglected facility so that it might better care for its patients.
New AmsterdamandHouseboth took a critical look at the flaws in the medical system, though from different angles. Dr. Max Goodwin, like House, was willing to break rules to prioritize patient care, but while House did so out of intellectual defiance, Max was driven by optimism and a desire to fix a broken system,based on the true story of Eric Manheimer. Dr. Goodwin’s approach of eliminating bureaucracy and putting patients first mirrored House’s belief that red tape often gets in the way of real medicine.
WhileNew Amsterdamhad a more hopeful, emotionally uplifting tone, it still scratches the same itch for viewers who enjoy medical dramas that challenge hospital norms. With five seasons,New Amsterdamdelivered a more heartfelt but equally rebellious take on reforming healthcare.
The Pitt
The Pitt is a gripping drama set in Pittsburgh’s Trauma Medical Center, where dedicated staff tirelessly work to save lives in a busy and underfunded emergency department. Released in 2025, the series highlights the challenges and relentless efforts of medical professionals in a high-pressure environment.
The Pittoffers a startlingly realistic portrayal of working in an emergency room, making it a great follow-up forHousefans who appreciated the show’s medical accuracy, no matter how absurd the cases became. WhileHouseoften used puzzle-like diagnostics,The Pittdoubles down on realism, capturing the chaotic and relentless pace of an emergency room.
Its real-time storytelling style, reminiscent of24, also calls to mindHouse’s special episodes that broke format, like “5 to 9”, which followed Dr. Cuddy’s nonstop day running the hospital. By immersing viewers in the intense, moment-to-moment challenges faced by medical professionals,The Pittoffers a gripping, authentic, and immersive experiencethat mirrors House’s commitment to showing the highs and lows of medicine. Season 1 is still airing, and the show has already been a huge hit for Max, which has renewedThe Pittfor season 2.
Pure Genius
Pure Genius follows a young Silicon Valley tech entrepreneur who partners with a surgeon with a controversial background to establish a new hospital that implements pioneering medical practices. Released in 2016, the series explores the intersection of technology and healthcare innovation.
Pure GeniussharedHouse’s fascination with medical innovation and pushing the boundaries of what’s possible in healthcare. InPure Genius, a billionaire tech visionary and maverick surgeon partnered to challenge the traditional medical system, clearing bureaucratic obstacles to prioritize patient care. WhileHousefocused on diagnostics,Pure Geniusleaned into futuristic medicine, using cutting-edge technology that does not yet exist.
20 Best House Episodes, Ranked
The House M.D. series wrapped over a decade ago, but the show is still one of the best medical dramas around, these are the best episodes.
Both shows balanced melodrama with humor, withPure Geniusembracing a sci-fi edgewhereHouserelied on cynical realism. Though the show only lasted one season, its bold vision and commitment to medical problem-solving make it worth checking out, especially forHousefans who enjoyed watching brilliant minds defy convention to save lives.
The Resident
The Resident is a medical drama that follows a senior resident named Conrad Hawkins and other staff members at Chastain Park Memorial Hospital. The series provides a look into the practices of the healthcare industry that are frequently scrutinized by those who must participate, as well as the personal lives of the staff as they attempt to juggle an increasingly difficult work/life balance.
If you rooted for House when he pushed boundaries for the sake of his patients, you’ll appreciateThe Resident.Matt Czuchry’s Dr. Conrad Hawkinswas a passionate and rebellious doctor who often challenged hospital protocol and authority to ensure the best care for his patients, regardless of the consequences. Like House, Dr. Hawkins frequently clashed with the hospital’s corporate interests and bureaucratic obstacles.
The Residentbalanced its intense medical drama with plenty of romantic tension and relationship dynamics, making ita great choice for viewers who enjoy both emotional depth and steamy love storieslikeChase and Cameron’s relationship inHouse. For 107 episodes over six seasons, the doctors inThe Residentfought for what’s right, even when it meant defying the system while navigating their personal lives in an engaging mix of drama and romance.
Transplant
Transplant follows Dr. Bashir Hamed, a Syrian doctor who flees his war-torn homeland, seeking to rebuild his medical career and new life at a busy emergency department in Canada.
TransplantandHousewereboth grounded medical dramas that highlight the brilliance and resilience of unconventional doctors. WhileHousefollowed a prickly, rule-breaking genius,Transplantcentered on Dr. Bashir “Bash” Hamed, a deeply empathetic Syrian refugee rebuilding his medical career from the ground up. Bash’s journey offered a more emotionally resonant, humanistic tone thanHouse, but both series share a focus on complex cases, ethical dilemmas, and characters who challenge the status quo.
This Canadian series ran for four seasons and is a strong pick for fans of emotionally rich, character-driven medical storytelling with a sharp procedural core.
Bash’s background brought fresh perspective and urgency to patient care, much like House’s relentless pursuit of truth. This Canadian series ran for four seasons and is a strong pick for fans of emotionally rich, character-driven medical storytelling with a sharp procedural core.
Watson
Watson follows Dr. John Watson a year after Sherlock Holmes' demise as he leads a clinic for rare disorders. Despite his return to medical practice, Watson is drawn back into the mysteries and challenges of his past, suggesting that his association with Holmes is far from over.
WatsonandHouseshare clear DNA in their inspiration from Sherlock Holmes, thoughWatsonis more overt about the connection, as Dr. John Watson is the actual former partner of Sherlock himself. LikeHouse,Watsonfollows a case-of-the-week format with intriguing medical mysteries that Watson solves in brilliant, often cryptic ways, aided by a team he’s hand-selected. Both shows feature complex, emotionally guarded leads with a deep sense of justice, even if their methods are unconventional.
Watson Season 2: Confirmation, Cast, Story & Everything We Know
CBS' modern Sherlock Holmes reimagining, Watson, delivers a medical drama twist, and now the series has been renewed for a second season.
However,Watsonadds an overarching mystery involvingHolmes' nemesis Moriarty, whose return and motives create long-running tension. Fans ofHousewill find familiar rhythms inWatson, and now is a great time to jump in withWatsonseason 2 already confirmedwith season 1 still currently airing weekly.
House
House is a medical mystery drama in which the villain is typically a difficult-to-diagnose medical malady. It follows Dr. Gregory House (Hugh Laurie), a world-renowned disabled diagnostician with a notorious substance abuse issue. With his team of world-class doctors, House has built a reputation as one of the most brilliant doctors in the world - an especially impressive feat when taking into account that he rarely actually sees his patients.
