WARNING: SPOILERS ahead for Dexter: Original Sin episode 8.

Patrick Dempsey’s recent role in theDexterprequel seriesDexter: Original Sinmakes the fact that he’s not starring in the upcomingScream 7movie even more disappointing. Best known for his role onGrey’s Anatomy, Dempsey is one of the newcast members inDexter: Original Sin. He often shares the screen with Patrick Gibson’s budding serial killerDexter, originally played by Michael C. Hall, and Christian Slater’s Detective Harry Morgan. Together, they investigate a string of murders in 1991 Miami.

While Patrick Dempsey has historically starred as a leading man in rom-coms, action movies, and lighthearted dramas, the actor has taken a handful of darker, more horror-centric projects in recent years. He starred as a sheriff inEli Roth’s surprise horror hitThanksgiving(2023) and is currently a key character inDexter: Original Sin. Dempsey also famously starred as Homicide Detective Mark Kincaid inScream 3(2000) as Sidney Prescott’s love interest, but Patrick never returned to the franchise.

Dexter Morgan (Patrick Gibson) in Dexter: Original Sin and Dexter Morgan (Michael C. Hall) under plastic wrap in Dexter

Patrick Dempsey Plays Another Killer Villain In Dexter: Original Sin

Police Captain Aaron Spencer Turns Out To Be The Prequel Show’s Main Villain

Patrick Dempsey plays Miami Metro Homicide Captain Aaron Spencer inDexter: Original Sin, who appeared to be a well-respected family man before his true identity was revealed as a child killer.Spencer turns out to be the first main villain of theDexterprequel series, who kills a prominent judge’s son and kidnaps his own son, Nicky. After severing Nicky’s finger and sending it to Miami Metro, Spencer frames some local cartel members and incites a shootout, which left an officer shot in the neck and fighting for his life.

10 Biggest Timeline Inconsistencies & Plot Holes In Dexter: Original Sin

Dexter: Original Sin has 10 major inconsistencies with the main series' timeline, and it created some fairly major plot holes in Dexter’s later life.

While Spencer’s motivations aren’t yet revealed afterDexter: Original Sinepisode 8, it’s quite clear that he is the major villain in the prequel series. This shocking role arrives just a few years after he was revealed to be the serial killer inThanksgiving,establishing a modern pattern of Dempsey playing a lethal antagonist. Patrick Dempsey not beingcast inScream 7, which he was in talks to return to as Mark Kincaid, is a major letdown considering he could have continued this recent killer streak, potentially as Ghostface himself.

Patrick Dempsey as Mark Kincaid alongside an image of Ghostface wielding a bloody knife

Patrick Dempsey’s Recent Villain Roles Would Have Made His Scream 7 Role Even Better

Thanksgiving & Dexter: Original Sin Would Have Primed Him For Scream 7

As evidenced by nicknames like “Dr. McDreamy”, Patrick Dempsey was originally known for playing good guys throughout his career, which makes his recent string of villain roles intriguing.Mark Kincaid finally returning after 26 years would have been nothing but a positivefor theScreamhorror franchise, especially considering therestructuring of its cast after 2023’sScream VI.

Mark Kincaid nearly returned in 2011’sScream 4but did not due to filming aTransformersmovie. Now, Patrick Dempsey won’t return toScream 7since Joel McHale has been cast as Sidney’s husband, which feels like a missed opportunity after his murderousDexter: Original Sinrole.

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